HIV/TB Co-infection: Restoring Immunity in Early HIV Infection through Tuberculosis Treatment

Abstract

Human Immunodeficiency Virus (HIV) and Tuberculosis (TB) represent two of the most devastating infectious diseases worldwide, particularly when they occur as co-infections. HIV weakens host immunity, dramatically increasing susceptibility to Mycobacterium tuberculosis, while TB accelerates HIV disease progression by enhancing immune activation and viral replication. Early HIV infection presents a critical window of opportunity for immune restoration, especially when TB is promptly diagnosed and treated.