Novel Approaches for Overcoming Antibiotic Resistance in Bacterial Infections
Abstract
Antibiotic resistance poses a significant threat to global public health, undermining the effectiveness of traditional antibiotics in treating bacterial infections. In recent years, the emergence of multidrug-resistant pathogens has necessitated the exploration of novel approaches to combat this growing crisis. This abstract highlights innovative strategies and advancements in the field of antimicrobial research aimed at overcoming antibiotic resistance and improving treatment outcomes for bacterial infections. Traditional antibiotics primarily target essential bacterial processes, such as cell wall synthesis, protein synthesis, and nucleic acid replication. However, the widespread use and misuse of antibiotics have led to the development of resistance mechanisms, including enzymatic inactivation, target site modification, and efflux pumps, rendering many antibiotics ineffective against resistant strains. In response to this challenge, researchers have turned to alternative approaches that exploit novel targets and mechanisms of action to circumvent antibiotic resistance.
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