Development of Biomaterials for Controlled Drug Release

Abstract

The controlled release of drugs is a pivotal aspect of modern pharmaceutical science, enabling precise dosing, prolonged therapeutic effects, and reduced side effects. Biomaterials play a crucial role in this field, providing platforms for the design and fabrication of drug delivery systems with tailored release kinetics. This abstract provides an overview of recent advancements in the development of biomaterials for controlled drug release. Firstly, the rationale behind controlled drug release is elucidated, emphasizing the significance of maintaining drug concentrations within therapeutic windows while minimizing systemic exposure. Biomaterial-based drug delivery systems offer unique advantages, including biocompatibility, tunable degradation rates, and the ability to encapsulate diverse therapeutic agents. Next, various biomaterials utilized for controlled drug release are discussed, including polymers, hydrogels, lipids, and nanoparticles. These materials can be engineered to exhibit specific properties such as sustained release, triggered release in response to environmental stimuli, or targeted delivery to disease sites.